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bei ta luo er zhi liao yan zhong man xing chong xue xing xin li shuai jie 286 li de liao xiao guan cha
Author(s): 
Pages: 8-10
Year: Issue:  5
Journal: HARBIN MEDICAL JOURNAL

Keyword:  倍他洛尔β-受体阻滞剂心力衰竭临床治疗;
Abstract: 目的探讨β1受体阻滞剂倍他洛尔对严重充血性心血衰竭的治疗作用.方法观察286例并随访其中211例经充分抗心衰(强心剂、利尿剂及血管扩张剂)治疗无效或效果不显并有持续心动过速的严重慢性充血性心力衰竭患者,经服用β1受体阻滞剂倍他洛尔,首次剂量1mg,每日2次,3~5d后视心率、血压及病情可逐渐加量至2~5mg,每日2次.连续治疗第1、2周后分别评定心功能改善情况.结果286例中除5例无效外,余281例心功能明显改善,第2周未心功能改善一级者80例,改善二级者201例;总有效率98.25%,其中显效率(心功能改善二级者)占70.28%.加用倍他洛尔前平均心室率为117士12.5次/min;加用倍他洛尔后,两周末平均心室率为64.3士8.5次/min,明显低于加用倍他洛尔前的平均心室率(P<0.01).结论加用倍他洛尔联合治疗严重慢性充血性心力衰竭可获良好临床效果.在慢性充血性心力衰竭的长期治疗中,持续联合应用小剂量倍他洛尔是安全、有效的.
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