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Clinical analysis of 17 patients with drug hypersensitivity syndrome
Author(s): 
Pages: 463-464
Year: Issue:  8
Journal: JOURNAL OF CLINICAL DERMATOLOGY

Keyword:  超敏综合征药物不良反应;
Abstract: 目的:加深对药物超敏综合征的认识.方法:回顾分析17例药物超敏综合征患者的临床资料.结果:17例患者均以皮疹、发热为首发症状,于用药后2~6周发生;其中伴浅表淋巴结大者12例、肝细胞损害者16例、肺损害者2例、肾损害者1例、白细胞升高者13例、血嗜酸粒细胞增多者14例;可疑致病药物为:别嘌呤醇9例、卡马西平3例、氨苯砜(DDS)3例、解热镇痛药2例.结论:临床用药过程中,如出现高热、浅表淋巴结大、血细胞异常、嗜酸粒细胞明显增高、全身性皮疹、内脏损害者应高度警惕药物超敏综合征.
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