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Clinical effect of oral viaminate and topical tretinoin cream in acne
Author(s): 
Pages: 439-440
Year: Issue:  7
Journal: JOURNAL OF CLINICAL DERMATOLOGY

Keyword:  痤疮寻常维胺酯维A酸全反式;
Abstract: 目的:观察维胺酯胶囊和全反式维A酸霜(商品名:迪维霜)治疗寻常痤疮的疗效.方法:将寻常痤疮患者随机分成3组,A组口服维胺酯胶囊,外用0.025%迪维霜;B组外用0.025%迪维霜;C组口服多西环素(商品名:强力霉素),外用硫磺炉甘石洗剂.均各治疗6周.结果:A组对丘疹和脂溢的疗效优于B组和C组(P<0.05),对粉刺的疗效优于C组(P<0.001),对脓疱的疗效优于B组(P<0.05),对结节囊肿的疗效3组差异无显著性;综合疗效A组优于B组和C组(P<0.05);A组中中度痤疮患者的效果优于B组和C组(P<0.05),但对轻度痤疮3组差异无显著性.结论:口服维胺酯胶囊联合外用迪维霜治疗轻、中度痤疮疗效较好.
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