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Clinical staging and surgical treatment of skull base chordomas
Author(s): 
Pages: 358-362
Year: Issue:  5
Journal: CHINESE JOURNAL OF OTORHINOLARYNGOLOGY

Keyword:  颅底肿瘤脊索瘤肿瘤分期外科手术;
Abstract: 目的通过对61例颅底脊索瘤回顾性分析,简化原颅底脊索瘤分型并提出新的临床分期.方法颅底脊索瘤61例,典型脊索瘤58例,软骨型脊索瘤3例,男34例,女27例,男女之比为1.26∶ 1,年龄7~75岁,平均(38.44±13.61)岁.初诊患者40例,复发患者21例.术前或术后接受放射治疗26例.分期方法:鞍区型Ⅰ、Ⅱ、Ⅲ、Ⅳ期,斜坡型Ⅰ、Ⅱ、Ⅲ、Ⅳ期,广泛型只有Ⅳ期.随访时间12~206个月.结果 61例患者本院接受90例次手术,全切除7 例次,次全切除26例次,大部分切除41例次,部分切除16例次;Ⅱ、Ⅲ、Ⅳ期手术分别为21例、30例次、39例次;上方入路全切或次全切为18例次(37.5%),下方入路为23例次(54.8%).并发症上方入路21例(43.75%),下方入路为6例(14.27%).3、5、10年生存率分别为73.02%、62.60%、37.64%.结论颅底脊索瘤临床分型与分期结合可以更好的对病变进行定位、定量、指导手术入路选择、比较疗效、评估预后.
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