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Curative Effect of VE Combined with Folic Acid on Treatment of Ischemic Stroke Complicated with HHcy and its Influence on Neurological Function,Plasma Hcy Level
Author(s): 
Pages: 308-309
Year: Issue:  4
Journal: Haerbin Medical Journal

Keyword:  维生素E叶酸缺血性脑卒中伴高Hcy血症神经功能血Hcy水平;
Abstract: 目的 研究维生素E联合叶酸治疗缺血性脑卒中伴高血浆同型半胱氨酸(Hcy)血症(HHcy)疗效及对神经功能、血Hcy水平的影响.方法 将我院2014年3月至2016年3月收治的144例缺血性脑卒中伴高Hcy血症患者纳为研究对象,采用随机数字表法将其分为观察组(维生素E+叶酸,n=72)与对照组(叶酸,n=72),观察两组治疗前后内皮功能、血Hcy水平与神经功能得分.结果 治疗后,两组血清NO、NOS水平均显著上升,ET显著下降,观察组各指标上升或下降幅度更大(P<0.05);治疗后,两组血Hcy水平与NIHSS得分均显著下降,观察组下降幅度更大(P<0.05).结论 维生素E联合叶酸可显著改善缺血性脑卒中伴HHcy患者血管内皮功能,降低血Hcy水平,减少患者神经损伤,值得临床推广.
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