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Curative Effect Observation of Metroprolol Succinate Combined with Tongxinluo Capsule on Treatment of Aged Coronary Heart Disease with Premature Ventricular Contraction
Author(s): 
Pages: 340-341
Year: Issue:  4
Journal: Haerbin Medical Journal

Keyword:  通心络胶囊琥珀酸美托洛尔冠心病室性早搏;
Abstract: 目的 探讨琥珀酸美托洛尔联合通心络胶囊对老年冠心病室性早搏的疗效.方法 将118例老年冠心病室性早搏患者采用随机数字表法分为观察组和对照组,每组各59例.两组均予以琥珀酸美托洛尔治疗,观察组加用通心络胶囊.比较两组室性早搏改善状况,评估患者治疗前后胆固醇水平[总胆固醇(TC)、低密度脂蛋白(LDL-C)、氧化低密度脂蛋白(ox-LDL)],血管内皮功能指标水平[血管内皮生长因子(VEGF)、内皮素-1(ET-1)、血管性假血友病因子(vWF)].结果 ①观察组室性早搏改善状况优于对照组(P<0.05);②治疗2个月后,两组胆固醇指标(TC、LDL-C、ox-LDL)和血管内皮功能指标(ET-1、vWF)水平均低于治疗前(P<0.05),两组VEGF水平均高于治疗前(P<0.05),观察组变动幅度大于对照组(P<0.05).结论 通心络胶囊联合琥珀酸美托洛尔能降低患者胆固醇水平、改善其血管内皮功能,治疗老年冠心病室性早搏疗效确切.
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