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luo bo yu shun bo tong bu diao qiang fang liao dui iib-iiib qi gong jing ai lin chuang fen xi
Pages: 358-359
Year: Issue:  4
Journal: Haerbin Medical Journal

Keyword:  宫颈癌洛铂调强同步放疗;
Abstract: 目的 评价洛铂与顺铂在Ⅱb-Ⅲb期宫颈癌同步调强放疗中的近期疗效和毒副反应.方法 56例初治Ⅱb-Ⅲb期宫颈癌随机分为2组,对照组28例(洛铂10mg/m2每周同步化疗),观察组28例(顺铂30 mg/m2每周同步化疗),比较两组近期疗效与副反应.结果 洛铂组与顺铂组的有效率分别为96.43%与92.86%,两组比较差异无统计学意义(P>0.05);洛铂组的胃肠道反应低于顺铂组(39.29%vs.57.14%)(P<0.05);洛铂组与顺铂组骨髓抑制发生率分别为17.86%和14.29%,两组比较差异无统计学意义(P>0.05).结论 洛铂和顺铂同步调强放疗Ⅱb-Ⅲb期宫颈癌近期疗效无明显差异,洛铂消化道反应较低.
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