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A comparison of response between mycophenolate mofetil and cyclophosphamide therapy for lupus nephritis
Author(s): 
Pages: 636-638
Year: Issue:  10
Journal: JOURNAL OF CLINICAL DERMATOLOGY

Keyword:  霉酚酸酯环磷酰胺泼尼松肾炎狼疮性;
Abstract: 为了观察霉酚酸酯治疗狼疮性肾炎的疗效及安全性,设置霉酚酸酯+泼尼松为治疗组和环磷酰胺+泼尼松为对照组,对肾活检确诊为狼疮性肾炎的患者进行临床疗效对比观察.结果发现治疗组虽有半数患者对环磷酰胺耐药,但疗效仍与对照组相当(P>0.05),而泼尼松减量速度则比对照组快(P<0.01).提示霉酚酸酯治疗狼疮性肾炎的疗效优于环磷酰胺.
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