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Clinical analysis of risk factors of acute poisoning complicated with rhabdomyolysis
Author(s): Mei Huaxian, Li Yongsheng, Chen Zhengping, Huang Zhonghui, Liu Fengdan
Pages: 839-
842
Year: 2016
Issue:
12
Journal: New Chinese Medicine
Keyword: Poison; Rhabdomyolysis; Risk factor;
Abstract: objective To explore the risk factors of acute poisoning patients presenting with rhab-domyolysis (RM). Methods Clinical data of 195 patients with acute poisoning were retrospectively analyzed.According to the incidence of RM or not,all patients were divided into the RM and non-RM groups. Clinical data were statistically compared between two groups. The variables with statistical significance (P<0.05 ) were subject to multivariate logistic regression analysis. Results Among 195 patients with acute poisoning,44 patients developed RM with an incidence rate of 22.6%. Univariate analysis revealed that sex,age and serum lactic acid level did not significantly differ between two groups (all P>0.05 ). Drug category,serum sodium level,serum potassium level,APACHE Ⅱ score,whether complicated with coma,convulsion,infection,is-chemia and anoxia or not significantly differed between two groups (all P<0.05 ). Multivariate regression anal-ysis demonstrated that complicated with coma,convulsion,ischemia and anoxia were independent risk factors of acute poisoning complicated with RM. Conclusions The incidence of RM in patients diagnosed with acute poisoning is significantly correlated with coma,convulsion,ischemia and anoxia. Early prevention and treat-ment is of clinical significance for acute poisoning patients presenting with these complications.
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