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The safety comparison of the topical acne vulgaris preparations
Author(s): 
Pages: 305-306
Year: Issue:  5
Journal: JOURNAL OF CLINICAL DERMATOLOGY

Keyword:  寻常痤疮过氧化苯甲酰克林霉素红霉素阿达帕林维A酸;
Abstract: 局部外用药物是治疗轻度寻常痤疮的首选方案,本文比较了采用药物局部斑贴实验进行了常用的外用药物局部刺激性的评价.结果所有药物均有不同程度的皮肤刺激性,就局部刺激性来说,1%克林霉素凝胶是较优秀的,0.1%阿达帕林凝胶以及0.05%维A酸霜均是有较弱的刺激性,程度基本一致,1%克林霉素&0.025%维A酸霜也具有很好的耐受性,5%过氧化苯甲酰刺激性较明显,但当加入3%红霉素时可减少其局部刺激性.
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