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Analysis of related factors of early death after transcatheter arterial chemoembolization for patients with early-and middle-stage primary hepatocellular carcinoma
Author(s): Huang Shugui, Deng Jun, Wu Xingjie
Pages: 614-
617
Year: 2016
Issue:
9
Journal: New Chinese Medicine
Keyword: Primary hepatocellular carcinoma; Transcatheter arterial chemoembolization; Postoperative early death; Type of HCC blood supply;
Abstract: Objective To retrospectively analyze the clinical data of patients diagnosed with early-and middle-stage primary hepatocellular carcinoma (HCC)with early death after transcatheter arterial chemo-embolization (TACE)and investigate the factors related to postoperative early death after TACE.Methods Clinical data of patients diagnosed with early-and middle-stage primary HCC undergoing TACE were collected in the recent 5 years.Twenty six patients who died within 30 d after TACE were allocated into the study group, and 50 cases who survived within postoperative 30 d were recruited as normal controls.Sex,age,frequency of previous TACE,the incidence of pseudocapsule tumor before TACE,CT classification of liver cirrhosis,intrao-perative quantity of lipiodol use,superselective embolization of tumor-feeding arteries and type of arterial blood supply were obtained.SPSS 1 9.0 software package was used for univariate analysis.The factors with statistical significance were incorporated into the binary logistic regression analysis.Results Univariate analysis revealed that frequency of previous TACE,intraoperative quantity of lipiodol use,superselective embolization of tumor-feeding arteries and type of arterial blood supply significantly differed between the study and control groups (all P <0.05).Binary logistic regression analysis demonstrated that type of arterial blood supply and frequency of previous TACE were correlated with early death after TACE (both P <0.05).Conclusion Type of arterial blood supply and frequency of previous TACE are significant influencing factors of early death after TACE in patients with early-and middle-stage primary HCC.
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