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Primary adenocarcinoma of the epididymis:a case report and literature review
Author(s): Cai Xiurong, Li Xing, Wang Tiantian, Dong Min, Chen Zhanhong, Hong Yingfen, Lin Qu, Wu Xiangyuan
Pages: 637-
640
Year: 2016
Issue:
9
Journal: New Chinese Medicine
Keyword: Male; Adenocarcinoma; Epididymis; Treatment;
Abstract: Objective To analyze and summarize the palliative treatment of primary adenocarcinoma of epididymis and provide evidence for clinical therapy.Methods In this article,we reported one case of pri-mary adenocarcinoma of epididymis.A comprehensive literature search was performed in China national knowl-edge infrastructure (CNKI),Wanfang and Medline databases using the keywords of “primary adenocarcinoma of epididymis”in Chinese and “primary epididymal adenocarcinoma”or “primary adenocarcinoma of the epi-didymis”.Both English and Chinese language studies were eligible.Clinical data of patients diagnosed with primary adenocarcinoma of epididymis who received palliative treatment were collected and analyzed.Results The male patient aged 58 years was diagnosed with primary adenocarcinoma of epididymis and underwent radi-cal surgery combined with chemotherapy.Subsequently,he experienced repeated recurrence.The patient un-derwent lymph node dissection and multiple chemotherapy regimes.Among them,docetaxel plus carboplatin, and irinotecan plus lobaplatin chemotherapies yielded clinical efficacy.He survived for over 1 3 years following radical surgery for the primary adenocarcinoma of epididymis.Clinical data were obtained from a total of 37 ca-ses of primary adenocarcinoma of epididymis.Seven patients received palliative therapy after recurrence.Single palliative treatment (such as surgery,radiotherapy or chemotherapy alone)yielded low clinical efficacy, whereas combined palliative therapies could prolong the patients’survival to certain extent.Conclusions Pa-tients with primary adenocarcinoma of epididymis can obtain clinical benefits from combined palliative therapies after recurrence.Physicians should comprehensively evaluate the patients’physical conditions and consider the advantages and disadvantages to determine whether the patients can undergo palliative treatment.
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