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Analysis of the clinical characteristics and related factors of dermatomyositis/polymyositis patients complicated with nosocomial infections
Author(s): 
Pages: 557-560
Year: Issue:  8
Journal: Journal of Clinical Dermatology

Keyword:  dermatomyositispolymyositisnosocomial infection;
Abstract: Objective: To explore the clinical characteristics and related factors of dermatomyositis(DM)/polymyositis(PM)patients complicated with nosocomial infections. Methods: Seventy-five inpatients with DM/PM were retrospectively analyzed.Results: Seventy-five DM/PM patients were hospitalized for 186 times. Nosocomial infection occurred in 89 times(47.8%).The upper respiratory tract infection was the most common(28.1%), followed by lung(25.8%) and skin mucosa(12.4%).Among the pathogens of nosocomial infections, there were 28 strains of gram-negative bacteria(53.9%), 20 strains of grampositive bacteria(38.5%), and 4 strains of fungi(7.6%). Pseudomonas aeruginosa(17.3%), Klebsiella pneumoniae(13.5%), and Staphylococcus aureus(9.7%) were on the top list of pathogenic bacteria. The drug sensitivity test showed that gram-negative bacteria were sensitive to amikacin, aztreonam and imipenem with less resistance. In contrast, gram-positive bacteria were sensitive to vancomycin and clindamycin with low rate of resistance. The risk factors for nosocomial infection included the length of hospital stay, steroid and immunosuppressive therapy, serum albumin levels, diabetes mellitus and invasive operation.Conclusion: The incidence of nosocomial infections is high in DM/PM patients, and the main pathogens are gram-negative bacteria. Appropriate measures should be taken to prevent nosocomial infections, and to accelerate recovery.
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