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Research progress on osteopetrosis
Author(s): 
Pages: 286-289
Year: Issue:  5
Journal: New Chinese Medicine

Keyword:  OsteopetrosisClinical typingVirulence geneHematopoietic stem cell transplantation;
Abstract: Osteopetrosis is a rare inherited metabolic bone disease due to the decreased quantity of osteoclasts or bone function deficiency.Up to date,1 2 types of virulence genes have been reported to link to osteopetrosis.Osteopetrosis is characterized with increased bone density and bone deformity.Clinical features vary according to the disease type.Osteopetrosis should be distinguished from skeletal fluorosis,systemic mul-tiple osteoblastic metastasis and renal osteopathy.At present,no standard therapy has been explored for the treatment of osteopetrosis,and hematopoietic stem cell transplantation is the only effective treatment.In this paper,research progress on osteopetrosis was briefly introduced to provide evidence for clinical treatment.
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