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A case of follicular mucinosis
Pages: 366-368
Year: Issue:  5
Journal: Journal of Clinical Dermatology

Keyword:  follicular mucinosisalopecia;
Abstract: A case of follicular mucinosis is reported. A 32-year-old woman presented with erythema on her head, face and back, and alopecia appeared on her scalp for half a year. Physical examination showed 3 nail-sized localized alopecia areas on her head with desquamation, and different size erythema on her face and back with mild desquamation. Histopathological examination showed slight hyperkeratosis and parakeratosis in the epidermis with thickened spinous layer and irregular elongation of the rete ridges, and mild lymphocytic infiltration around blood vessel and hair follicles in the dermis. The hair follicles were obvious degenerative and formation of localized cavities filled with mucous-like materials. Mucin staining(+), acidfast staining(-). Immunohistochemical examination showed LCA(+), focal CD3 and CD20(+), CD4(-), and CD75(-). Using nested PCR with two pairs of primers, T-cell receptor gene rearrangement study showed polyclonal features. Diagnosis: follicular mucinosis. Treatment: Polysaccharide selenate capsules, vitamin E capsules, mizolastine tablets were prescribed. Dexamethasone cream and zinc oxide ointment were topically used. Four months later, the lesions disappeared without recurrence up to date.
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