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Clinical efficacy of subcutaneous pruning and curettage treatment for axillary osmidrosis: Meta analysis
Pages: 829-834
Year: Issue:  12
Journal: Journal of Clinical Dermatology

Keyword:  axillary osmidrosissubcutaneous pruningsubcutaneous curettagerandomized controlled trialsMeta-analysis;
Abstract: Objective: To systemically assess the effectiveness of subcutaneous pruning and curettage for the treatment of axillary osmidrosis. Methods: The domestic and foreign literatures were retrieved by computer to collect all the randomized controlled clinical trials(RCT) on subcutaneous pruning and subcutaneous curettage for the treatment of axillary osmidrosis.The quality of the included studies was evaluated, and Meta-analysis was performed using Rev Man 5.2 software. Results: A total of 12 Chinese RCT were included, they were 1 288 sites of axillae treated with subcutaneous pruning, and 1 389 sites of axillae treated with subcutaneous curettage. The results of the Meta-analysis indicated that the curative rate of subcutaneous pruning was obviously superior to that of subcutaneous curettage(OR=4.00, P=0.004), and the recurrence rate was lower than that of subcutaneous curettage(OR=0.31, P<0.000 01). The differences of effective rate, complication rates(hematoma formation, infection, necrosis of the skin or flap, wound dehiscence and scar formation) between the two groups were not statistically significant(P >0.05). Conclusion: Compared with subcutaneous curettage, subcutaneous pruning for the treatment of axillary osmidrosis has the advantages of high cure rate and low recurrence rate, and safe and feasible. Due to the small sample size and low quality of the included studies, further well-designed RCT should be performed.
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