The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit later.
We apologize for any inconvenience caused
Login  | Sign Up  |  Oriprobe Inc. Feed
China/Asia On Demand
Journal Articles
Laws/Policies/Regulations
Companies/Products
A retrospective study of the impact of diabetes mellitus on survival in patients with lung cancer
Author(s): 
Pages: 1028-1031
Year: Issue:  12
Journal: Chinese Journal of Internal Medicine

Keyword:  Diabetes mellitusLung neoplasmsSurvival;
Abstract: Objective To investigate the impact of diabetes mellitus (DM) on survival in patients with lung cancer.Methods This is a retrospective study of 1 096 patients died from lung cancer collected from clinical records in Chinese PLA General Hospital.Survival time of lung cancer with and without DM was compared using Log-rank analysis and Cox regression model.Results One hundred and eighty-one patients (16.5%) had DM.The median survival time of the lung cancer patients with DM was 9 months,whereas,the median survival time of the patients without DM was 8 months.Log-rank analysis showed that this difference was significant (P < 0.05).Moreover,the 1-,2-,and 3-year survival rate in lung cancer patients with and without DM were 43% vs 35%,27% vs 17%,and 16% vs 10%,respectively.After adjusting for age,gender,histology,stage of lung cancer and treatment,Cox regression analysis showed that the hazard ratio for survival in lung cancer patients with DM was 0.74 (95% CI 0.61-0.89,P < 0.05) compared with those without DM.In non-small-cell lung cancer (NSCLC) patients,the hazard ratio for survival in lung cancer patients with DM was 0.69 (95% CI 0.56-0.85,P <0.05).However,this association disappeared in small-cell lung cancer (SCLC) patients.In advanced lung cancer patients (stage Ⅲ-Ⅳ),diabetes was also a significant factor for survival (HR =0.74,95% CI 0.61-0.91,P < 0.05).Conclusion Patients with advanced NSCLC with DM have longer survival time compared with those without DM.
Related Articles
No related articles found