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Clinical features and significance of coronary tortuosity
Author(s): 
Pages: 777-780
Year: Issue:  11
Journal: New Chinese Medicine

Keyword:  Coronary tortuosityLeft ventricular diastolic functionCoronary angiographyHypertension;
Abstract: Objective To investigate the clinical features and significance of coronary tortuosity. Methods One hundred and sixty-one patients with no apparent stenosis in coronary angiography were recruited as study subjects and assigned into the coronary tortuosity (n =79)and non-tortuosity groups (n =82).All subjects received ultrasound cardiogram (UCG)to assess the left ventricular diastolic function.Clinical fea-tures and risk factors of coronary tortuosity were retrospectively analyzed to explore its clinical significance.Re-stults The incidence of coronary tortuosity in left circumflex artery was 62.0% and 57.6% for single coronary tortuosity.In the coronary tortuosity group,the mean arterial pressure (MAP),interventricular septal thick-ness (IVST),isovolumetric relaxation time (IVRT),deceleration time of E velocity (DT),late transmitral inflow (A)velocity and E /E′ratio were significantly higher (all P <0.05),whereas the early transmitral in-flow (E)velocity,early mitral annular inflow (E′)velocity and E /A ratio were considerably lower compared with those in the non-tortuosity group (all P <0.05).Logistic regression analysis revealed that the elevation of MAP,IVST,DT and E /E′and the decrease of E /A might be risk factors of coronary tortuosity(all P <0.05). Conclusions The left circumflex artery is a preponderant site of coronary tortuosity,and the incidence of sin-gle coronary tortuosity is high.Coronary tortuosity might be an indicator of impaired left ventricular diastolic function and intimately associated with blood pressure.
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