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Clinical efficacy and safety of compound clobetasol propionate for neurodermatitis and chronic eczema
Author(s): 
Pages: 320-322
Year: Issue:  5
Journal: Journal of Clinical Dermatology

Keyword:  compound clobetasol propionateneurodermatitischronic eczema;
Abstract: Objective: To observe the clinical efficacy and safety of compound clobetasol propionate for the treatment of neurodermatitis and chronic eczema. Methods: 240 patients with neurodermatitis and 210 patients with chronic eczema were divided into three groups. Patients in the treatment group were treated with compound clobetasol propionate while group treated with 0.05% clobetasol propionate served as control group 1, and those treated with 0.025% tretinoin served as control group2. Treatments were given twice daily for 4 weeks. Results: Both cure rate and effective rate in the treatment group were higher than that in the control groups(P<0.01). The incidence of adverse reaction in both treatment group and control 1 group was lower than that in the control 2 group. Conclusion: Compound clobetasol propionate is an effective and safe topical agent for neurodermatitis and chronic eczema.
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