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Ambulatory blood pressure monitoring in patients with obstructive sleep apnea-related refractory hypertension
Author(s): 
Pages: 115-118
Year: Issue:  2
Journal: New Chinese Medicine

Keyword:  Obstructive sleep apneaRefractory hypertensionAmbulatory blood pressure monitoringPolysomnographyBlood pressure variability;
Abstract: 目的 了解阻塞性睡眠呼吸暂停(OSA)相关性难治性高血压(RH)患者动态血压特点.方法 将89例RH患者根据OSA的有无及程度分为非OSA组、轻度OSA组和中重度OSA组,比较3组患者动态血压指标,包括血压负荷、血压波动曲线、日间及夜间平均血压和血压变异.结果 中重度OSA组患者血压负荷明显高于其他2组,3组患者日间平均收缩压比较差异无统计学意义,而日间舒张压、夜间收缩压及舒张压随OSA程度加重逐渐升高.3组患者日间收缩压及舒张压变异比较差异无统计学意义.随着OSA程度加重,非杓形曲线发生率、夜间血压变异逐渐增加,而杓形曲线发生率逐渐减少.结论 OSA的存在和加重会使RH患者日间舒张压、夜间血压水平升高并增加夜间血压波动,对心血管系统产生不利影响.
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