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Application of Raman Spectroscopy for Analysis in Radiosensitivity of Total Protein of Nasopharygeal Carcinoma Cells
Author(s): 
Pages: 107-110,106
Year: Issue:  1
Journal: Acta Laser Biology Sinica

Keyword:  Raman spectroscopynasopharyngeal carcinoma cellstotal proteinsupport vector machine;
Abstract: To study the effects of total protein of nasopharyngeal carcinoma cell line CNE2 treated by different doses of X-ray irradiation.The total protein is extracted from the cell line and detected by confocal micro-Raman spectroscopy. Both t test and support vector machine are employed via SPSS and LIBSVM software packages for statistical analysis of Raman spectrum.The results show that several Raman bands assigned to total protein can be detected;and the X-ray ir-radiation have various effects on different components in total protein,and related to the radiation dose.It was indicated
that in spite of no significant diversification on structures of protein,the content may be varied during irradiation.

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