A propose to suspend the use of hydroxyethyl starch for fluid resuscitation in shock phase of severe burns
Author(s): LUO Gao-xing, PENG Yi-zhi, WU Jun
Pages: 421-423
Year: 2013 Issue: 5
Journal: Chinese Journal of Burns
Keyword: Burns; Hetastarch; Shock;
Abstract: Based on the result of randomized controlled trials and meta-analysis recently,the infusion of hydroxyethyl starch(HES)was not shown to overmatch routine crystalline solution in exerting resuscitation effect against hypovolemia of patients with burn shock,severe systematic infection,or other critical conditions,on the other hand,it may induce renal toxicity and other toxic and side effects.Since the pathological mechanism underlying hypovolemia during shock phase after burn is similar to that of severe systemic infection,we propose to suspend the use of HES for fluid resuscitation during the shock phase of severe burn until further elucidation.
Pages: 421-423
Year: 2013 Issue: 5
Journal: Chinese Journal of Burns
Keyword: Burns; Hetastarch; Shock;
Abstract: Based on the result of randomized controlled trials and meta-analysis recently,the infusion of hydroxyethyl starch(HES)was not shown to overmatch routine crystalline solution in exerting resuscitation effect against hypovolemia of patients with burn shock,severe systematic infection,or other critical conditions,on the other hand,it may induce renal toxicity and other toxic and side effects.Since the pathological mechanism underlying hypovolemia during shock phase after burn is similar to that of severe systemic infection,we propose to suspend the use of HES for fluid resuscitation during the shock phase of severe burn until further elucidation.
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