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xian tian xing ju jie chang de shen jing di zhi zuo lei ji su ding liang yan jiu
Author(s): 
Pages: 21-22
Year: Issue:  12
Journal: Journal of Medical Research

Keyword:  先天性巨结肠神经节细胞神经递质病理生理机制痉挛状态肠梗阻小儿外科平滑肌收缩状态副交感神经;
Abstract: <正> 先天性巨结肠(HD)是小儿外科常见病,其病理基本病变是神经节细胞缺如,病理生理变化是神经节细胞缺如肠段平滑肌过度收缩呈痉挛状态,蠕动消失,以致肠腔内粪便不能通过痉挛部位,临床上出现肠梗阻或便秘症状。为什么神经节细胞缺如的肠段一定呈收缩状态,国外虽有一些研究,但仍不能解释清楚。本研究从神经递质、肠神经肽测定着手,以揭示先天性巨结肠病理生理机制。
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