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Photochemical Mechanism of R-phycoerythrin Mediated Photodynamic Therapy of Cancer
Author(s): 
Pages: 116-119
Year: Issue:  2
Journal: ACTA LASER BIOLOGY SINICA

Keyword:  藻红蛋白肿瘤光动力治疗光漂白;
Abstract: To explore the photochemical mechanisms of R-phycoery thrin mediated Photodynamic therapy of cancer,the photobleaching was observed wi th different concentrations of R-PE and inhibitors of reactive oxygen species.T he results show that it will decrease the efficacy of PDT when the R-PE concent ration reached one top concentration.And the mechanisms involved in R-PE mediat ed PDT include Ⅰ and Ⅱ type reactive oxygen production reaction.The inhibitor of Ⅰ type reaction made more singlet oxygen produced by transition from Ⅰ to Ⅱ type with more efficiency.
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