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The in vitro diagnosis of cutaneous drug allergy
Author(s): 
Pages: 59-61
Year: Issue:  1
Journal: Journal of Clinical Dermatology

Keyword:  皮肤药物变态反应;
Abstract: 体外试验是验证皮肤药物变态反应的有力证据,由于其安全性强,敏感性和特异性较高,是皮肤试验和激发试验的有力补充.主要有血清特异性IgE检测、嗜碱性粒细胞活化试验(BAT)、淋巴细胞转化试验(LTT)、淋巴细胞活化试验(LAT)、细胞毒性试验、细胞因子检测试验,用于诊断IgE介导的速发型药物变态反应和非IgE(主要由T细胞)介导的迟发型药物变态反应.该文主要综述了各种体外试验运用在皮肤药物变态反应中的研究进展,为临床诊治提供指导.
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