xiao shu gan zang que xue zai guan zhu sun shang hou janus ji mei / xin hao zhuan dao zi ji zhuan lu ji huo zi tong lu ji yin biao da de bian hua
Author(s): WANG Zejun, MA Han, XU Chengfu, SHI Qiaojuan, YU Chaohui, LI Youming
Pages: 777-778
Year: 2012 Issue: 11
Journal: Chinese Journal of Digestion
Abstract: 肝脏缺血再灌注(ischemia reperfusion,I/R)损伤是造成肝脏手术患者术后恢复慢甚至手术失败的重要原因.肝脏I/R损伤的发生涉及众多基因和蛋白表达的变化,Janus激酶/信号转导子及转录激活子(Janus kinase/signal transducer and activator of transcription,JAK/STAT)通路近年来备受关注,是重要的细胞内信号转导途径,在肝脏I/R损伤中的作用尚未明确.本研究利用基因芯片技术分析小鼠肝脏I/R损伤后JAK/STAT通路基因表达的变化,以期为认识肝脏I/R损伤的发生机制提供新的线索.
Pages: 777-778
Year: 2012 Issue: 11
Journal: Chinese Journal of Digestion
Abstract: 肝脏缺血再灌注(ischemia reperfusion,I/R)损伤是造成肝脏手术患者术后恢复慢甚至手术失败的重要原因.肝脏I/R损伤的发生涉及众多基因和蛋白表达的变化,Janus激酶/信号转导子及转录激活子(Janus kinase/signal transducer and activator of transcription,JAK/STAT)通路近年来备受关注,是重要的细胞内信号转导途径,在肝脏I/R损伤中的作用尚未明确.本研究利用基因芯片技术分析小鼠肝脏I/R损伤后JAK/STAT通路基因表达的变化,以期为认识肝脏I/R损伤的发生机制提供新的线索.
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