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Endoscopic ultrasound guided fine needle aspiration in combination with flow cytometry in the diagnosis of gastrointestinal lymphoma
Author(s): XU Ying, ZHANG Shu-xian, WANG Shu-bei, XIA Lu, WENG Xiang-qin, YE Ting-jun, ZHU Qi, SUN Yun-wei
Pages: 735-
740
Year: 2012
Issue:
11
Journal: Chinese Journal of Digestion
Keyword: Gastrointestinal neoplasms; Lymphoma; Endoscopy; Flow cytometry; Aspiration biopsy; fine-needle;
Abstract: 目的 评价超声内镜引导下细针穿刺(EUS-FNA)联合流式细胞术(FCM)对淋巴瘤的诊断价值.方法 回顾性分析2011年1月至12月上海瑞金医院收治的疑似淋巴瘤患者,行EUS-FNA且穿刺标本行FCM检测,以手术或活组织检查病理和随访结果为最终诊断,初步分析EUS-FNA联合FCM对淋巴瘤诊断的灵敏度、特异度、准确度.结果 共收集14例疑似淋巴瘤患者,最终经手术病理或活组织检查病理确诊为淋巴瘤8例,非淋巴瘤性病变4例,2例患者未得到最终诊断.单独依靠FCM对淋巴瘤诊断的灵敏度均为4/8,特异度为4/4.EUS-FNA联合FCM检出淋巴瘤6例,对淋巴瘤诊断的灵敏度为6/8,特异度为4/4,准确度为10/12.结论 EUS-FNA联合FCM对淋巴瘤具有较好的诊断价值,尤其对于胃肠道及其周边深部病变更具显著优势.
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