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Effects of Gymnadenia conopse achohol extract on early protein profiles in lung tissue of rats exposed to silica
Author(s): 
Pages: 432-435
Year: Issue:  6
Journal: Chinese Journal of Industrial Hygiene and Occupational Diseases

Keyword:  Silicon dioxidePlant extractsPulmonary fibrosis;
Abstract: 目的 应用比较蛋白质组学方法分析手掌参醇提取物对染尘大鼠早期肺组织蛋白表达的影响,以寻找低毒有效的矽肺防治药物并初步探讨手掌参干预后的分子机制.方法 随机将Wistar大鼠分为染尘组和手掌参干预组,每组4只,气管暴露法给予1 ml SiO2混悬液(50 mg/ml)建立大鼠模型.染尘后第2天,干预组给予手掌参醇提取物按0.8 g/100 g(0.8 ml/100 g)的量每天灌胃,染尘组给予蒸馏水...
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