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Screening of differentially expressed serum proteins in patients with asbestosis
Author(s): 
Pages: 408-412
Year: Issue:  6
Journal: Chinese Journal of Industrial Hygiene and Occupational Diseases

Keyword:  AsbestosisSerumProteomicsImmune system;
Abstract: 目的 分离和鉴定石棉肺患者、石棉接触正常人群及未接触石棉正常对照人群的血清差异表达蛋白质,以期进一步探索发病机制及筛选潜在生物标志物.方法 以石棉肺患者37人作为石棉肺组,以曾进行石棉作业的健康工人254人作为阴性对照组,以该地区未接触石棉的439人作为正常对照组.采用蛋白质组学方法对3组人群血清蛋白进行分离和鉴定.结果 获得各组人群血清蛋白质凝胶图谱,分析发现石棉肺组同正常对照组比较,差异点≥1...
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