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Effects of electromagnetic pulse exposure on the morphological change and excretion function of BV-2 cells and possible mechanism
Author(s): YANG Long-long, ZHOU Yan, LI Hai-juan, GUO Juan, ZHANG Yan-jun, DING Gui-rong, GUO Guo-zhen
Pages: 163-
167
Year: 2012
Issue:
3
Journal: Chinese Journal of Industrial Hygiene and Occupational Diseases
Keyword: Electromagnetic fields; Microglia; Reactive oxygen species; Nitric oxide; Mitogen-activated protein kinases;
Abstract: 目的 研究电磁脉冲( electromagnetic pulse,EMP)对小鼠BV-2小胶质细胞形态及分泌功能的影响,并初步探讨其作用机制.方法 离体培养的BV-2细胞经200 kV/m EMP辐照200次,分别在辐照后1、6、12、24h收集细胞培养上清及细胞.倒置显微镜下观察细胞形态变化,ELISA法检测培养上清中肿瘤坏死因子-α(TN F-α)、白细胞介素(IL)-1β、IL-10等细胞因...
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