Author(s): LIU Feng, JIAN Xiang-dong, ZHANG Zhong-chen, LIU Hui-min, ZHOU Qian, ZHANG Wei, SHANG Bo, TIAN Dong, NIU Yan-ying, BI Yan-qun, JIANG Jian
Pages: 190-193
Year: 2012 Issue:  3
Journal: Chinese Journal of Industrial Hygiene and Occupational Diseases
Keyword:  Paraquat; Heparin; low-molecular-weight; Aspirin;
Abstract: 目的 建立百草枯中毒急性肺损伤模型,观察低分子肝素钙联合阿司匹林治疗百草枯中毒急性肺损伤的疗效.方法 120只成年雄性Wistar大鼠,随机分为3组,百草枯染毒组一次性给予百草枯50 mg/kg灌胃；抗凝治疗组一次性给予百草枯50 mg/kg灌胃,再给予低分子肝素钙68 U/kg,2次/d,皮下注射,同时给予阿司匹林1.67 mg/kg灌胃,1次/d,给药至动物处死前；对照组给予等量生理盐水灌胃....