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Measurement and Prediction of Solubility of S-Timolol-D-Tartrate Salt in Organic Solvents
Pages: 7-12
Year: Issue:  1
Journal: Journal of Chemical Engineering of Chinese Universities

Keyword:  溶解度S-噻吗洛尔-D-酒石酸非对映体盐UNIFAC法基团贡献;
Abstract: 实验测定了S-噻吗洛尔-D-酒石酸非对映体盐(S-TTS)在乙醇、正丙醇、丙酮、l,2-二氯乙烷和乙酸乙酯中的溶解度.在相同温度下,S-TTS在这些溶剂中的溶解度(s)顺序是:S(乙(-))>S(正丙醇)>S(丙酮)>S(1.2(-*.Ⅷ)>S(乙酸乙(m)).用四参数多项式、Apelblat方程、改进的Apelblat方程和λH方程关联了溶解度实验数据,以四参数多项式关联实验数据的结果最好,其相...
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