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Effect of ulinastatin on oxidative stress and nuclear factor E2-related factor 2 expression in the lung tissues of acute hydrogen sulfide intoxicated rats
Author(s): GE Yun, SUN Wei, WU Zong-sheng, JIANG Xiao-zhen, QIU Qiao-meng, HONG Guang-liang, LIANG Huan, LI Meng-fang, LU Zhong-qiu
Pages: 27-
32
Year: 2012
Issue:
1
Journal: Chinese Journal of Industrial Hygiene and Occupational Diseases
Keyword: Hydrogen sulfide; Transcription factors; Acute lung injury; Ulinastratin;
Abstract: 目的 研究硫化氢急性中毒大鼠肺组织氧化应激水平及核转录因子NF-E2相关因子2(nuclear factor E2-related factor 2,Nrf2)基因表达的变化及乌司他丁(ulinastatin,UTI)的影响.方法 将96只清洁级SD大鼠随机分为正常对照组(8只)、UTI对照组(8只)、硫化氢染毒组(40只)、UTI干预组(40只).正常对照组和UTI对照组大鼠于染毒柜内吸人与硫化...
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