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Effects of dexamethasone or tacrolimus on expression of heat shock protein 90 of HaCaT cells in vitro
Pages: 11-13
Year: Issue:  1
Journal: Journal of Clinical Dermatology

Keyword:  地塞米松他克莫司角质形成细胞热休克蛋白;
Abstract: 目的:比较地塞米松和他克莫司对HaCaT 细胞热休克蛋白90(HSP90)表达的影响,并探讨其潜在的临床意义.方法:以含10-6 mol/L 地塞米松或10-6 mol/L 他克莫司的DMEM(高糖)培养基培养细胞,在24 h 和48 h 的不同时相点,采用Real timePCR和Western blotting 检测HSP90 的表达.结果:地塞米松作用24 h 后,HSP90 mRNA和蛋白...
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