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The developmental neurotoxic effects in offspring of pregnant rats exposed to benzo[a]pyrene
Author(s): 
Pages: 275-279
Year: Issue:  4
Journal: Chinese Journal of Industrial Hygiene and Occupational Diseases

Keyword:  Benzo[a]PyreneMaternal-fetal exchangeNeurobehavioral man ifestations;
Abstract: 目的 研究孕期暴露苯并(a)芘(B[a]P)对子代大鼠生理发育、早期行为发育、对环境的适应能力及学习记忆能力的影响.方法 SD孕鼠随机分为未处理对照组(每日正常饲养)、溶剂对照组(橄榄油)、低剂量组(25mg/kgB[a]P)、中剂量组(50mg/kgB[a]P)、高剂量组(100mg/kg B[a]P),于妊娠第17天开始,每天1次腹腔注射染毒,连续3 d,待其自然分娩.仔鼠出生后第1、4、7、...
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