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Design and biological evaluation of poly-lactic-co-glycolic acid(PLGA) mesh/collagen-chitosan hybrid scaffold (CCS) as a dermal substitute
Author(s): 
Pages: 16-20
Year: Issue:  1
Journal: Chinese Journal of Burns

Keyword:  RegenerationPoly-lactic-co-glycolic acidCollagen-chitosan;
Abstract: 目的 设计并构建一种含有编织网的连续性真皮再生模板,并初步评价其生物学性能.方法 采用冷冻-冻干法将聚乳酸-羟基乙酸(PLGA)编织网整合到胶原-壳聚糖支架(CCS)中,形成PLGA编织网/胶原-壳聚糖复合支架(PCCS),对比PLGA编织网、PCCS、CCS微观形态及机械强度.将PCCS及CCS分别埋植于18只SD大鼠皮下(PCCS组、CCS组,每组9只大鼠).术后1、2、4周取埋植部位皮肤标本...
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