The effects of ammonium perchlorate on thyroid function and mRNA expression of thyroglobulin and thyroperoxidase
Author(s): WU Feng-hong, ZHOU Xuan, ZHANG Rao, PAN Mei-zhu, PENG Kai-liang
Pages: 83-86
Year: 2011 Issue: 2
Journal: Chinese Journal of Industrial Hygiene and Occupational Diseases
Keyword: Ammonium perchlorate; Thyroid gland; Thyroid hormones; Thyroglobulin; Iodide peroxidase;
Abstract: 目的 研究过氯酸铵(AP)对大鼠甲状腺功能及甲状腺球蛋白(Tg)、甲状腺过氧化物酶(TPO)基因mRNA表达的影响.方法 将雄性SD大鼠30只随机分为:正常对照组、低碘组(含碘量:50μg/kg)、AP染毒低(130 mg/kg)、中(260 mg/kg)、高剂量组(520 mg/kg)及AP+高碘组[AP:520 mg/kg,高碘饮水(10 mg/L)],每组5只.经口染毒90 d后处死,放射免...
Pages: 83-86
Year: 2011 Issue: 2
Journal: Chinese Journal of Industrial Hygiene and Occupational Diseases
Keyword: Ammonium perchlorate; Thyroid gland; Thyroid hormones; Thyroglobulin; Iodide peroxidase;
Abstract: 目的 研究过氯酸铵(AP)对大鼠甲状腺功能及甲状腺球蛋白(Tg)、甲状腺过氧化物酶(TPO)基因mRNA表达的影响.方法 将雄性SD大鼠30只随机分为:正常对照组、低碘组(含碘量:50μg/kg)、AP染毒低(130 mg/kg)、中(260 mg/kg)、高剂量组(520 mg/kg)及AP+高碘组[AP:520 mg/kg,高碘饮水(10 mg/L)],每组5只.经口染毒90 d后处死,放射免...
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