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The efficacy and safety of valproic acid in combination with low dose chemotherapy on intermediate and high-risk myelodysplastic syndrome
Author(s): ZHANG Qing-yi, GE Gui-min, YAN Yi-peng, HAN Xiao-lin, HUANG Yan, WU Sun, HE Li-shan
Pages: 240-
242
Year: 2011
Issue:
3
Journal: Chinese Journal of Internal Medicine
Keyword: Myelodysplastic syndrome; Valproic acid; Treatment outcome; Safety; Low dose chemotherapy;
Abstract: 目的 观察丙戊酸(VPA)联合小剂量化疗治疗中高危骨髓增生异常综合征(MDS)的疗效和安全性.方法 回顾性分析2007年6月至2009年6月41例初治MDS患者,19例采用小剂量化疗,22例采用VPA联合小剂量化疗.小剂量化疗方案:中危组采用静脉滴注高三尖杉酯碱1~2mg/d,14~28 d;或皮下注射阿糖胞苷15 mg/m2,每12小时1次,14~21 d;或阿克拉霉素5~7 mg·m-2·d-...
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