Author(s): PENG Lijun, GUO Jinsheng, WANG Jiyao
Pages: 925-928
Year: 2010 Issue:  12
Journal: Chinese Journal of Digestion
Abstract:  基因多态性(genetic polymorphisms)普遍存在,如单个碱基的缺失和插入、短串联重复序列、单核苷酸多态性(single nucleotide polymorphism,SNP)等.其中SNP是最常见的基因多态性,指一个碱基的替换.人类全基因组中约有一千万个SNP,其等位基因频率不低于1%.