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The study on screening the differences of serum proteins in ulcerative colitis
Author(s): 
Pages: 898-901
Year: Issue:  12
Journal: Chinese Journal of Digestion

Keyword:  Ulcerative colitisSerumTwo-dimensional gel electrophoresisSpectrometrymassmatrix-assisted laser desorption-ionization;
Abstract: 目的 应用蛋白质组学寻找溃疡性结肠炎(UC)血清差异蛋白,初步探索UC可能的生物标志物.方法 收集UC患者30例和健康对照者30名的血清标本,双向凝胶电泳(2-DE)分离等量混合血清的蛋白质,运用图像分析软件进行比较和分析,识别差异表达蛋白质.应用基质辅助激光解吸/电离飞行时间质谱(MALDI-TOF-MS)鉴定部分差异蛋白质点.结果 UC组和对照组之间年龄、体重指数、吸烟情况和饮酒量的差异均无统...
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