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Study on the Pharmacokinetic of Nitrobenzene in Urine after Exposure the Cow by Mouth Successively Many Times
Author(s): SONG Wei-feng
Pages: 49-
51
Year: 2010
Issue:
10
Journal: China Dairy Cattle
Keyword: 高效液相色谱; 硝基苯; 代谢物; 氨基酚; 硝基苯胺; 硝基酚;
Abstract: 本文以高效液相色谱(High Performance Liquid Chromatography,HPLC)作为硝基苯在奶牛体内主要代谢产物的定量手段,采用MCPKP自动化药动学分析程序分析其浓度-时间数据,以不同剂量硝基苯,通过奶牛自由饮水持续经口染毒,分别研究了硝基苯的三种主要代谢产物氨基酚、硝基苯胺和硝基酚在奶牛尿液中的动态变化规律和残留消除规律.结果表明,奶牛尿液中只有代谢产物氨基酚,说明...
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