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Association of the single nucleotide polymorphism and the serum contents of interleukine-18 with ulcerative colitis
Author(s): 
Pages: 78-80
Year: Issue:  2
Journal: Chinese Journal of Digestion

Keyword:  Ulcerative colitisInterleukin-18Single nucleotide polymorphism;
Abstract: 目的 探讨白细胞介素(IL)-18基因单核苷酸多态性(SNP)及其血清含量与溃疡性结肠炎(UC)的相关性.方法 采用PCR扩增和直接测序法检测50例UC患者及128名健康对照者的IL-18基因5\'端4个SNP位点(rs187238 G/C、rs5744228 G/A、rs360718 A/C、rs360717 G/A),同时检测受试者血清IL-18含量.结果 UC组血清IL-18含量明显高于对照组...
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