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zeng zhi xi bao he kang yuan he xi bao zhou qi su d yi lai xing ji mei 4 zai ru fang wai paget bing zhong de biao da he yi yi
Author(s): 
Pages: 14-16
Year: Issue:  1
Journal: Journal of Clinical Dermatology

Keyword:  核抗原增殖细胞细胞周期素D依赖性激酶4Paget病乳房外免疫组化;
Abstract:  乳房外Paget病(extramammary Paget\'s disease,EMPD)又称乳房外湿疹样癌,是一种少见的恶性皮肤肿瘤,其发病机制尚不完全清楚.细胞周期调控异常是细胞癌变的重要机制之一.CDK4即细胞周期素D依赖性激酶4,是细胞周期蛋白依赖性蛋白激酶(cyclin-dependent kinases,CDKs)家族成员之一.是细胞周期G,期的正调控因子.
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