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Study on the Characteristics of the Pathogen of Cow Endometritis in Shanxi Province
Author(s): Han Yichao, Wu Shouyan
Pages: 41
Year: 2009
Issue:
1
Journal: China Dairy Cattle
Keyword: 奶牛; 子宫内膜炎; 病原特性; 灭活疫苗; 免疫;
Abstract: 本研究对山西省部分奶牛养殖场、户的奶牛进行子宫内膜炎病原菌的分离、鉴定和进行致病性的研究,并研究出子宫内膜炎灭活疫苗,同时对该疫苗的免疫原性进行研究,结果表明,这些奶牛场的奶牛子宫内膜炎的病原菌以大肠杆菌和奇异变形杆菌为主,分别占47.1%和27.1%;接种大肠杆菌和奇异变形杆菌的小白鼠72 h全部死亡:将这两种细菌研制成灭活疫苗后,接种牛群,抗体效价高峰时达到1:512,高峰期维持63d,然后开始下降.经84d逐渐下降到1:64.本课题组自行研制的灭活疫苗的免疫原性好,为奶牛子宫内膜炎的生物防制奠定了良好的基础.
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