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Human papillomavirus type 2 induced multiple huge verrucae vulgaris associated with cutaneous horns:a report of three cases
Author(s): 
Pages: 84-87
Year: Issue:  2
Journal: JOURNAL OF CLINICAL DERMATOLOGY

Keyword:  寻常疣皮角人乳头瘤病毒-2a;
Abstract: 目的:探讨巨大寻常疣并发多发巨大皮角的治疗及其与人乳头瘤病毒(HPV)亚型的相关性.方法:对3例手足巨大寻常疣并发对称性巨大皮角的患者采用抗病毒、手术、免疫、放疗和中药等综合治疗,同时应用免疫组化和PCR等方法研究其中2例患者皮损与HPV感染亚型的相关性.结果:3例患者的皮损全部治愈,随访至今无复发;其中2例患者的皮损均为HPV-2a感染,并发现编码E1和E7的基因存在突变.结论:巨大寻常疣并发皮角宜采用综合治疗.
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