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Advances of dendritic cell subtypes in the pathophysiology of atopic dermatitis
Author(s): 
Pages: 336-338
Year: Issue:  5
Journal: JOURNAL OF CLINICAL DERMATOLOGY

Keyword:  皮炎特应性树突状细胞髓样树突状细胞浆细胞样;
Abstract: 特应性皮炎(AD)的病理生理学特征是在急性期以Th2细胞免疫应答为主,慢性湿疹期则有Th1细胞参与.AD患者皮肤和血液中有2种树突状细胞,即髓样树突状细胞和浆细胞样树突状细胞.朗格汉斯细胞和炎性表皮树突状细胞表面均有高表达的IgE高亲和力受体,浆细胞样树突状细胞在防御病毒感染中起保护作用.2种树突状细胞在AD的发病中可能起重要作用.
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