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Effect of occupationally exposed to dioxin on serum oxidative stress indices in male workers
Author(s): 
Pages: 419-422
Year: Issue:  7
Journal: CHINESE JOURNAL OF INDUSTRIAL HYGIENE AND OCCUPATIONAL DISEASES

Keyword:  二噁英丙二醛谷胱甘肽过氧化酶超氧化物歧化酶;
Abstract: 目的探讨职业接触二噁英对男工血浆中氧化应激指标的影响.方法以职业接触二噁英的作业男工为暴露组和没有该职业接触史的人群为对照组,分别测定血浆中丙二醛(MDA)含量,谷胱甘肽过氧化酶(GSH-Px)和超氧化物歧化酶(SOD)活力.结果与对照组相比,暴露组血浆中MDA含量明显增高,差异有统计学意义(P<0.01),提示工人体内可能发生了脂质过氧化;同时抗氧化系统中SOD和GSH-Px活力均出现下降趋势,但仅有后者的下降差异有统计学意义(P<0.05).结论职业性接触二噁英对男工血浆中氧化应激指标具有一定的干扰作用.
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