Study on Quality Standards of Wudajiangjun Tincture
Author(s): SU Qing, LEI Pei-lin, HUANG Rui-song, Guangxi Academy of Minority Nationality Medicine and Pharmacology
Pages: 620-626
Year: 2015 Issue: 6
Journal: Guangxi Sciences
Keyword: Wudajiangjun Tincture; quality standards; TLC; HPLC;
Abstract: 【Objective】The quality standards for Wudajiangjun Tincture were established in order to guarantee its safety and effectivity in clinical treatment.【Methods】Thin layer chromatograms(TLC)method was used for qualitative identification of extracts from the tincture,including giant knotweed rhizome,zedoray rhizome,sichuan lovage rhizome,paniculate swallowwort root,Resina draconis,mentha-camphor and other medicinal materials qualitative.High performance liquid chromatography(HPLC)method was used to quantitatively determine active ingredients of the tincture such as polydatin and paeonol.【Results】Characteristics of TLC spots for the abovementioned 6medicinal materials were clear separation and concentrated.In HPLC method,agood linear relationship between sample content and peak area was received when the reference substance of polydatin was ranged from 0.1to 0.7μg,and when paeonol concentration was within the range of 0.052 to 0.364μg.【Conclusion】The scientific quality standards of Wudajiangjun Tincture are successfully established,which can be used to effectively control the product quality for Zhuang medicine preparations of Wudajiangjun Tincture.
Pages: 620-626
Year: 2015 Issue: 6
Journal: Guangxi Sciences
Keyword: Wudajiangjun Tincture; quality standards; TLC; HPLC;
Abstract: 【Objective】The quality standards for Wudajiangjun Tincture were established in order to guarantee its safety and effectivity in clinical treatment.【Methods】Thin layer chromatograms(TLC)method was used for qualitative identification of extracts from the tincture,including giant knotweed rhizome,zedoray rhizome,sichuan lovage rhizome,paniculate swallowwort root,Resina draconis,mentha-camphor and other medicinal materials qualitative.High performance liquid chromatography(HPLC)method was used to quantitatively determine active ingredients of the tincture such as polydatin and paeonol.【Results】Characteristics of TLC spots for the abovementioned 6medicinal materials were clear separation and concentrated.In HPLC method,agood linear relationship between sample content and peak area was received when the reference substance of polydatin was ranged from 0.1to 0.7μg,and when paeonol concentration was within the range of 0.052 to 0.364μg.【Conclusion】The scientific quality standards of Wudajiangjun Tincture are successfully established,which can be used to effectively control the product quality for Zhuang medicine preparations of Wudajiangjun Tincture.
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