Experimental Study on Hypoglycemic Effect of Longchi Tablet
Author(s): SUN Hui-jing, SU Heng-hai, LI Li, ZHOU Jing, The People’s Hospital of Guangxi Zhuang Autonomous Region, Guangxi University of Chinese Medicine
Pages: 641-645
Year: 2015 Issue: 6
Journal: Guangxi Sciences
Keyword: Longchi tablets; hypoglycemic effect; animal experiment;
Abstract: 【Objective】Longchi Tablet（LC tablet）is a clinical prescription from Doctor Zhu-quan Yu in the People’s Hospital of the Guangxi Zhuang Autonomous Region,and its hypoglycemic effects on normal mice and the mice from several diabetes models were studied.【Methods】The diabetic hyperglycemia models of mice were induced by streptozotocin（STZ）,adrenaline（AD）and glucose,respectively.The impacts of LC tablet on the level of blood sugar were observed in normal mice and the mice of diabetes models.【Results】High and middle doses of LC tablet(11500mg·kg-1·d-1 and 5750mg·kg-1·d-1)significantly reduced the blood sugar levels in the diabetes mice induced by STZ and in the mice with hyperglycemia induced by AD and high-dose oral glucose;But high and low doses of LC tablet(11500 mg·kg-1·d-1 and 3060mg·kg-1·d-1)had no significant effect on blood glucose levels of the normal mice（P >0.05）.【Conclusion】LC tablet has the effect of lowering blood sugar in diabetic model mice.
Pages: 641-645
Year: 2015 Issue: 6
Journal: Guangxi Sciences
Keyword: Longchi tablets; hypoglycemic effect; animal experiment;
Abstract: 【Objective】Longchi Tablet（LC tablet）is a clinical prescription from Doctor Zhu-quan Yu in the People’s Hospital of the Guangxi Zhuang Autonomous Region,and its hypoglycemic effects on normal mice and the mice from several diabetes models were studied.【Methods】The diabetic hyperglycemia models of mice were induced by streptozotocin（STZ）,adrenaline（AD）and glucose,respectively.The impacts of LC tablet on the level of blood sugar were observed in normal mice and the mice of diabetes models.【Results】High and middle doses of LC tablet(11500mg·kg-1·d-1 and 5750mg·kg-1·d-1)significantly reduced the blood sugar levels in the diabetes mice induced by STZ and in the mice with hyperglycemia induced by AD and high-dose oral glucose;But high and low doses of LC tablet(11500 mg·kg-1·d-1 and 3060mg·kg-1·d-1)had no significant effect on blood glucose levels of the normal mice（P >0.05）.【Conclusion】LC tablet has the effect of lowering blood sugar in diabetic model mice.
Related Articles