Progress of burn research in metabolism and nutrition in China
Author(s): WANG Shi-liang
Pages: 396-399
Year: 2008 Issue: 5
Journal: CHINESE JOURNAL OF BURNS
Keyword: Burns; Nutrition; Metabolism;
Abstract: The achievements of burn metabolism and nutrition in China are briefly presented. Advance a new theory "Enterogenous Hypermetabolism". Develop a formula to calculate calorie needs in Chinese burn adults. Put forward new ideas on glucose absorption, neoglycogenesis, insulin resistance, and the use of hypoglycemic agent after burn inury. Observe the variation of plasma level of free aminoacids, investigate the changes and mechanisms of 26S proteasome and 19S regulator in skeletal muscle of burn trauma, and the clinical application and its mechanism of glutamine and arginine. Introduce the approach of 13 C NMR spectroscopy to investigate the alterations of hepatic anabolism functions in severely burned rats. Offer supplying the suitable dosage of vitamin A,C,E and microeiement of zinc, copper, ferrum for burn patients. Carry out serial studies of early enteral and parenteral nutrition, and compare enteral nutrition with parenteral nutrition. Early ehteral nutrition with synbiotics might be beneficial to the controlling of burn infection. Both glucagon like peptide-2(GLP-2) and intestinal trefoil factor(ITF) exhibit protective effect on intestinal mucosa in minimizing injury and protecting barrier function. The choice of suitable opportunity to use rhGH (growth hormone) is investigated. In addition, advance the view points of isehemia and anoxia in metabolism, anti-inflammatory immune and nutrition.
Pages: 396-399
Year: 2008 Issue: 5
Journal: CHINESE JOURNAL OF BURNS
Keyword: Burns; Nutrition; Metabolism;
Abstract: The achievements of burn metabolism and nutrition in China are briefly presented. Advance a new theory "Enterogenous Hypermetabolism". Develop a formula to calculate calorie needs in Chinese burn adults. Put forward new ideas on glucose absorption, neoglycogenesis, insulin resistance, and the use of hypoglycemic agent after burn inury. Observe the variation of plasma level of free aminoacids, investigate the changes and mechanisms of 26S proteasome and 19S regulator in skeletal muscle of burn trauma, and the clinical application and its mechanism of glutamine and arginine. Introduce the approach of 13 C NMR spectroscopy to investigate the alterations of hepatic anabolism functions in severely burned rats. Offer supplying the suitable dosage of vitamin A,C,E and microeiement of zinc, copper, ferrum for burn patients. Carry out serial studies of early enteral and parenteral nutrition, and compare enteral nutrition with parenteral nutrition. Early ehteral nutrition with synbiotics might be beneficial to the controlling of burn infection. Both glucagon like peptide-2(GLP-2) and intestinal trefoil factor(ITF) exhibit protective effect on intestinal mucosa in minimizing injury and protecting barrier function. The choice of suitable opportunity to use rhGH (growth hormone) is investigated. In addition, advance the view points of isehemia and anoxia in metabolism, anti-inflammatory immune and nutrition.
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